High-dose green tea polyphenols induce nephrotoxicity in dextran sulfate sodium-induced colitis mice by down-regulation of antioxidant enzymes and heat-shock protein expressions.

Inoue, Hirofumi; Akiyama, Satoko; Maeda-Yamamoto, Mari; Nesumi, Atsushi; Tanaka, Takuji; Murakami, Akira

Inoue, Hirofumi; Akiyama, Satoko; Maeda-Yamamoto, Mari; Nesumi, Atsushi; Tanaka, Takuji; Murakami, Akira.

Affiliation

Inoue H; Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Japan.

Cell Stress Chaperones ; 16(6): 653-62, 2011 Nov.

Article in En | MEDLINE | ID: mdl-21766215

Subject(s)

Antioxidants/metabolism; Colitis/chemically induced; Heat-Shock Proteins/genetics; Kidney/drug effects; Polyphenols/toxicity; Tea/toxicity; Animals; Dextran Sulfate; Down-Regulation/drug effects; Heme Oxygenase-1/genetics; Kidney/metabolism; Lipid Peroxidation/drug effects; Liver/drug effects; Male; Mice; Organ Size/drug effects; Polyphenols/administration & dosage; RNA, Messenger/genetics

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Full text: 1 Database: MEDLINE Main subject: Tea / Colitis / Polyphenols / Heat-Shock Proteins / Kidney / Antioxidants Language: En Journal: Cell Stress Chaperones Year: 2011 Type: Article Affiliation country: Japan

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