Activation of TRPA1 by membrane permeable local anesthetics.

Leffler, Andreas; Lattrell, Anja; Kronewald, Sergej; Niedermirtl, Florian; Nau, Carla

Leffler, Andreas; Lattrell, Anja; Kronewald, Sergej; Niedermirtl, Florian; Nau, Carla.

Affiliation

Leffler A; Department of Anesthesiology, Friedrich-Alexander-University Erlangen-Nuremberg, Krankenhausstrasse 12, 91054 Erlangen, Germany.

Mol Pain ; 7: 62, 2011 Aug 23.

Article in En | MEDLINE | ID: mdl-21861907

Subject(s)

Anesthetics, Local/pharmacology; Cell Membrane Permeability/drug effects; Ion Channel Gating/drug effects; Transient Receptor Potential Channels/metabolism; Animals; Ankyrins/metabolism; Calcium/pharmacology; Calcium Channels/metabolism; HEK293 Cells; Humans; Intracellular Space/drug effects; Intracellular Space/metabolism; Lidocaine/analogs & derivatives; Lidocaine/pharmacology; Mice; Mustard Plant; Mutant Proteins/metabolism; Nerve Tissue Proteins/metabolism; Plant Oils/pharmacology; Rats; TRPA1 Cation Channel; TRPC Cation Channels; TRPM Cation Channels/metabolism

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Full text: 1 Database: MEDLINE Main subject: Ion Channel Gating / Cell Membrane Permeability / Transient Receptor Potential Channels / Anesthetics, Local Language: En Journal: Mol Pain Year: 2011 Type: Article Affiliation country: Germany

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