(-)-epigallocatechin-3-O-gallate augments pentobarbital-induced sleeping behaviors through Cl- channel activation.

Park, Kwang-Soon; Han, Jin-Yi; Moon, Dong-Cheul; Hong, Jin Tae; Oh, Ki-Wan

Park, Kwang-Soon; Han, Jin-Yi; Moon, Dong-Cheul; Hong, Jin Tae; Oh, Ki-Wan.

Affiliation

Park KS; Medical Research Center (MRCT), College of Pharmacy, Chungbuk National University, Cheongju, Korea.

J Med Food ; 14(11): 1456-62, 2011 Nov.

Article in En | MEDLINE | ID: mdl-21883003

Subject(s)

Catechin/analogs & derivatives; Chloride Channels/metabolism; Chlorides/metabolism; Neuroprotective Agents/pharmacology; Pentobarbital/pharmacology; Sleep/drug effects; Animals; Catechin/pharmacology; Cells, Cultured; Cerebellum/cytology; Cerebellum/drug effects; Cerebellum/metabolism; Glutamate Decarboxylase/metabolism; Hippocampus/drug effects; Male; Mice; Mice, Inbred ICR; Muscimol/pharmacology; Rats; Rats, Sprague-Dawley; Receptors, GABA/metabolism

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Full text: 1 Database: MEDLINE Main subject: Pentobarbital / Sleep / Catechin / Chlorides / Chloride Channels / Neuroprotective Agents Language: En Journal: J Med Food Year: 2011 Type: Article

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