The EPI bioassay identifies natural compounds with estrogenic activity that are potent inhibitors of androgenic pathways in human prostate stromal and epithelial cells.

Vollmer, Günter; Helle, Janina; Amri, Hakima; Liu, Xunxian; Arnold, Julia T

Vollmer, Günter; Helle, Janina; Amri, Hakima; Liu, Xunxian; Arnold, Julia T.

Affiliation

Vollmer G; Technische Universität Dresden, Molecular Cell Physiology & Endocrinology, Dresden, Germany. guenter.vollmer@tu-dresden.de

J Steroid Biochem Mol Biol ; 129(3-5): 153-62, 2012 Apr.

Article in En | MEDLINE | ID: mdl-22207083

Subject(s)

Androgen Antagonists/pharmacology; Biological Products/pharmacology; Drug Evaluation, Preclinical/methods; Isoflavones/pharmacology; Prostate/cytology; Prostate/drug effects; Receptors, Estrogen/agonists; Androgens/metabolism; Cell Line, Tumor; Cells, Cultured; Coculture Techniques/methods; Dehydroepiandrosterone/metabolism; Epithelial Cells/drug effects; Epithelial Cells/metabolism; Humans; Male; Prostate/metabolism; Prostate-Specific Antigen/metabolism; Glycine max/chemistry; Stromal Cells/drug effects; Stromal Cells/metabolism

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Full text: 1 Database: MEDLINE Main subject: Prostate / Biological Products / Receptors, Estrogen / Drug Evaluation, Preclinical / Androgen Antagonists / Isoflavones Type of study: Guideline / Prognostic_studies Language: En Journal: J Steroid Biochem Mol Biol Year: 2012 Type: Article Affiliation country: Germany

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