Effects of Hura crepitans and its active ingredient, daphne factor F3, on dihydrotestosterone-induced neurotrophin-4 activation and hair retardation.

Uchiyama, Chiyoko; Ishida, Kazuhiro; Tsutsui, Takuya; Naito, Atsushi; Kurita, Kei; Hanihara, Hiroyuki; Serizawa, Tetsushi; Fujiwara, Masami; Ohdera, Motoyasu

Uchiyama, Chiyoko; Ishida, Kazuhiro; Tsutsui, Takuya; Naito, Atsushi; Kurita, Kei; Hanihara, Hiroyuki; Serizawa, Tetsushi; Fujiwara, Masami; Ohdera, Motoyasu.

Affiliation

Uchiyama C; Pharmaceutical Research Laboratories No. 1, Lion Corporation; 100 Tajima, Odawara, Kanagawa 2560811, Japan.

Biol Pharm Bull ; 35(1): 42-7, 2012.

Article in En | MEDLINE | ID: mdl-22223335

Subject(s)

Alopecia/drug therapy; Diterpenes/therapeutic use; Euphorbiaceae/chemistry; Hair/drug effects; Nerve Growth Factors/metabolism; Phytotherapy; Transcriptional Activation/drug effects; Alopecia/genetics; Alopecia/metabolism; Animals; Dihydrotestosterone/metabolism; Diterpenes/isolation & purification; Diterpenes/pharmacology; Hair/growth & development; Hair/metabolism; HeLa Cells; Humans; Male; Mice; Mice, Inbred C57BL; Nerve Growth Factors/antagonists & inhibitors; Nerve Growth Factors/genetics; Plant Extracts/chemistry; Plant Extracts/pharmacology; Plant Extracts/therapeutic use; Transcription, Genetic/drug effects

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Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas Main subject: Transcriptional Activation / Euphorbiaceae / Diterpenes / Alopecia / Hair / Phytotherapy / Nerve Growth Factors Language: En Journal: Biol Pharm Bull Year: 2012 Type: Article Affiliation country: Japan

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