Comparative pharmacokinetics of prim-O-glucosylcimifugin and cimifugin by liquid chromatography-mass spectrometry after oral administration of Radix Saposhnikoviae extract, cimifugin monomer solution and prim-O-glucosylcimifugin monomer solution to rats.

Li, Yueyue; Zhao, Liang; Zhang, Hai; Jia, Jing; Lv, Lei; Zhou, Guichen; Chai, Yifeng; Zhang, Guoqing

Li, Yueyue; Zhao, Liang; Zhang, Hai; Jia, Jing; Lv, Lei; Zhou, Guichen; Chai, Yifeng; Zhang, Guoqing.

Affiliation

Li Y; Department of Pharmacy, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.

Biomed Chromatogr ; 26(10): 1234-40, 2012 Oct.

Article in En | MEDLINE | ID: mdl-22253022

Subject(s)

Apiaceae/chemistry; Chromatography, Liquid/methods; Chromones/pharmacokinetics; Drugs, Chinese Herbal/pharmacokinetics; Mass Spectrometry/methods; Monosaccharides/pharmacokinetics; Xanthenes/pharmacokinetics; Administration, Oral; Animals; Chromones/administration & dosage; Chromones/blood; Chromones/chemistry; Drug Stability; Drugs, Chinese Herbal/administration & dosage; Linear Models; Male; Monosaccharides/administration & dosage; Monosaccharides/blood; Monosaccharides/chemistry; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Xanthenes/administration & dosage; Xanthenes/blood; Xanthenes/chemistry

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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Mass Spectrometry / Xanthenes / Drugs, Chinese Herbal / Chromatography, Liquid / Chromones / Apiaceae / Monosaccharides Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: Biomed Chromatogr Year: 2012 Type: Article Affiliation country: China

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