Polymeric human Fc-fusion proteins with modified effector functions.

Mekhaiel, David N A; Czajkowsky, Daniel M; Andersen, Jan Terje; Shi, Jianguo; El-Faham, Marwa; Doenhoff, Michael; McIntosh, Richard S; Sandlie, Inger; He, Jianfeng; Hu, Jun; Shao, Zhifeng; Pleass, Richard J

Mekhaiel, David N A; Czajkowsky, Daniel M; Andersen, Jan Terje; Shi, Jianguo; El-Faham, Marwa; Doenhoff, Michael; McIntosh, Richard S; Sandlie, Inger; He, Jianfeng; Hu, Jun; Shao, Zhifeng; Pleass, Richard J.

Affiliation

Mekhaiel DN; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK.

Sci Rep ; 1: 124, 2011.

Article in En | MEDLINE | ID: mdl-22355641

Subject(s)

Immunoglobulin Fc Fragments/metabolism; Animals; B-Lymphocytes/immunology; B-Lymphocytes/metabolism; Base Sequence; Biological Therapy; Complement System Proteins/metabolism; DNA Primers/genetics; Female; Histocompatibility Antigens Class I/metabolism; Humans; Immunization; Immunoglobulin Fc Fragments/chemistry; Immunoglobulin Fc Fragments/genetics; Immunoglobulin Fc Fragments/therapeutic use; Immunoglobulin G/chemistry; Immunoglobulin G/genetics; Immunoglobulin G/metabolism; Malaria/immunology; Malaria/parasitology; Malaria/therapy; Mice; Mice, Inbred BALB C; Models, Molecular; Plasmodium berghei; Protein Binding; Protein Multimerization; Receptors, Fc/metabolism; Receptors, IgG/metabolism; Recombinant Fusion Proteins/chemistry; Recombinant Fusion Proteins/genetics; Recombinant Fusion Proteins/metabolism; Recombinant Fusion Proteins/therapeutic use

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Full text: 1 Database: MEDLINE Main subject: Immunoglobulin Fc Fragments Type of study: Prognostic_studies Language: En Journal: Sci Rep Year: 2011 Type: Article Affiliation country: United kingdom

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