Fragment informatics and computational fragment-based drug design: an overview and update.

Sheng, Chunquan; Zhang, Wannian

Sheng, Chunquan; Zhang, Wannian.

Affiliation

Sheng C; Department of Medicinal Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai, 200433, People's Republic of China. shengcq@hotmail.com

Med Res Rev ; 33(3): 554-98, 2013 May.

Article in En | MEDLINE | ID: mdl-22430881

Subject(s)

Computational Biology/methods; Drug Design; 14-alpha Demethylase Inhibitors/chemical synthesis; Catalytic Domain; Cyclophilin A/antagonists & inhibitors; Drug Evaluation, Preclinical/methods; Ligands; Molecular Docking Simulation; Nitric Oxide Synthase Type I/antagonists & inhibitors; Receptors, Drug/chemistry; Serotonin 5-HT1 Receptor Antagonists/chemical synthesis; Software; Structure-Activity Relationship

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Drug Design / Computational Biology Language: En Journal: Med Res Rev Year: 2013 Type: Article

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Drug Design / Computational Biology Language: En Journal: Med Res Rev Year: 2013 Type: Article