Myosin light-chain kinase is necessary for membrane homeostasis in cochlear inner hair cells.

Zhu, Guang-Jie; Wang, Fang; Chen, Chen; Xu, Lin; Zhang, Wen-Cheng; Fan, Chi; Peng, Ya-Jing; Chen, Jie; He, Wei-Qi; Guo, Shi-Ying; Zuo, Jian; Gao, Xia; Zhu, Min-Sheng

Zhu, Guang-Jie; Wang, Fang; Chen, Chen; Xu, Lin; Zhang, Wen-Cheng; Fan, Chi; Peng, Ya-Jing; Chen, Jie; He, Wei-Qi; Guo, Shi-Ying; Zuo, Jian; Gao, Xia; Zhu, Min-Sheng.

Affiliation

Zhu GJ; MOE Key Laboratory for Model Animal and Diseases Studies, Nanjing Drum Tower Hospital and Model Animal Research Center of Nanjing University, Nanjing, China.

PLoS One ; 7(4): e34894, 2012.

Article in En | MEDLINE | ID: mdl-22485190

Subject(s)

Cell Membrane/enzymology; Hair Cells, Auditory, Inner/enzymology; Homeostasis; Myosin-Light-Chain Kinase/physiology; Actin Cytoskeleton/metabolism; Actins/metabolism; Animals; Cell Membrane/metabolism; Epithelium/enzymology; Epithelium/metabolism; Evoked Potentials, Auditory, Brain Stem; Gene Expression; Hair Cells, Auditory, Inner/metabolism; Hair Cells, Auditory, Inner/ultrastructure; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Myosin Light Chains/metabolism; Myosin VIIa; Myosin-Light-Chain Kinase/deficiency; Myosin-Light-Chain Kinase/genetics; Myosins/metabolism; Organ of Corti/cytology; Osmotic Pressure; Phosphorylation; Protein Processing, Post-Translational; Sequence Deletion; Sodium-Potassium-Exchanging ATPase/genetics; Sodium-Potassium-Exchanging ATPase/metabolism

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Full text: 1 Database: MEDLINE Main subject: Myosin-Light-Chain Kinase / Cell Membrane / Hair Cells, Auditory, Inner / Homeostasis Language: En Journal: PLoS One Year: 2012 Type: Article Affiliation country: China

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