The relaxant effect of ginseng saponin on the bladder and prostatic urethra: an in vitro and in vivo study.

Jang, H A; Cho, S; Kang, S G; Ko, Y H; Kang, S H; Bae, J H; Cheon, J; Kim, J J; Lee, J G

Jang, H A; Cho, S; Kang, S G; Ko, Y H; Kang, S H; Bae, J H; Cheon, J; Kim, J J; Lee, J G.

Affiliation

Jang HA; Department of Urology, Korea University Hospital, Seoul, Republic of Korea.

Urol Int ; 88(4): 463-9, 2012.

Article in En | MEDLINE | ID: mdl-22507987

Subject(s)

Muscle Relaxation/drug effects; Muscle, Smooth/drug effects; Panax; Plant Extracts/pharmacology; Saponins/pharmacology; Urethra/drug effects; Urinary Bladder Neck Obstruction/drug therapy; Urinary Bladder/drug effects; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors/pharmacology; In Vitro Techniques; Male; Muscle, Smooth/metabolism; Muscle, Smooth/physiopathology; NG-Nitroarginine Methyl Ester/pharmacology; Nitric Oxide/metabolism; Nitric Oxide Synthase/antagonists & inhibitors; Nitric Oxide Synthase/metabolism; Panax/chemistry; Phenylephrine/pharmacology; Plant Extracts/isolation & purification; Plant Roots; Pressure; Prostatic Hyperplasia/complications; Prostatic Hyperplasia/metabolism; Prostatic Hyperplasia/physiopathology; Rabbits; Rats; Rats, Sprague-Dawley; Saponins/isolation & purification; Urethra/metabolism; Urethra/physiopathology; Urinary Bladder/metabolism; Urinary Bladder/physiopathology; Urinary Bladder Neck Obstruction/etiology; Urinary Bladder Neck Obstruction/metabolism; Urinary Bladder Neck Obstruction/physiopathology; Urodynamics/drug effects

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Full text: 1 Database: MEDLINE Complementary Medicines: Homeopatia Main subject: Saponins / Urethra / Urinary Bladder / Urinary Bladder Neck Obstruction / Plant Extracts / Panax / Muscle Relaxation / Muscle, Smooth Type of study: Etiology_studies Language: En Journal: Urol Int Year: 2012 Type: Article

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