Mechanisms of attenuation of abdominal sepsis induced acute lung injury by ascorbic acid.

Fisher, Bernard J; Kraskauskas, Donatas; Martin, Erika J; Farkas, Daniela; Wegelin, Jacob A; Brophy, Donald; Ward, Kevin R; Voelkel, Norbert F; Fowler, Alpha A; Natarajan, Ramesh

Fisher, Bernard J; Kraskauskas, Donatas; Martin, Erika J; Farkas, Daniela; Wegelin, Jacob A; Brophy, Donald; Ward, Kevin R; Voelkel, Norbert F; Fowler, Alpha A; Natarajan, Ramesh.

Affiliation

Fisher BJ; Division of Pulmonary and Critical Care Medicine, Dept. of Internal Medicine, Virginia Commonwealth University, Richmond, VA 23298-0050, USA.

Am J Physiol Lung Cell Mol Physiol ; 303(1): L20-32, 2012 Jul 01.

Article in En | MEDLINE | ID: mdl-22523283

Subject(s)

Acute Lung Injury/drug therapy; Ascorbic Acid/pharmacology; Sepsis/drug therapy; Abdomen/microbiology; Abdomen/pathology; Acute Lung Injury/metabolism; Acute Lung Injury/microbiology; Acute Lung Injury/physiopathology; Animals; Biomarkers/blood; Blood Coagulation/drug effects; Bronchoalveolar Lavage/methods; Cell Line; Cytoskeletal Proteins/metabolism; Humans; Inflammation/blood; Inflammation/metabolism; Inflammation/physiopathology; Ion Channels/metabolism; Ion Transport/drug effects; Lung/drug effects; Lung/metabolism; Lung/physiopathology; Male; Mice; Mice, Inbred C57BL; Neutrophils/drug effects; Neutrophils/metabolism; Neutrophils/physiology; Peritonitis/drug therapy; Peritonitis/metabolism; Peritonitis/microbiology; Peritonitis/physiopathology; Permeability/drug effects; Pulmonary Alveoli/drug effects; Pulmonary Alveoli/metabolism; Pulmonary Alveoli/physiopathology; Respiratory Mucosa/drug effects; Respiratory Mucosa/metabolism; Respiratory Mucosa/physiopathology; Sepsis/blood; Sepsis/metabolism; Sepsis/physiopathology; Sodium-Potassium-Exchanging ATPase/metabolism

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Full text: 1 Database: MEDLINE Main subject: Ascorbic Acid / Sepsis / Acute Lung Injury Language: En Journal: Am J Physiol Lung Cell Mol Physiol Year: 2012 Type: Article Affiliation country: United States

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