Alzheimer Disease/metabolism; Biomarkers, Tumor/metabolism; Carrier Proteins/metabolism; Citrulline/metabolism; Creutzfeldt-Jakob Syndrome/metabolism; DNA-Binding Proteins/metabolism; Hydrolases/metabolism; Phosphopyruvate Hydratase/metabolism; Tumor Suppressor Proteins/metabolism; Aged; Aged, 80 and over; Alzheimer Disease/pathology; Aminocaproic Acid/pharmacology; Animals; Antibodies, Monoclonal/immunology; Biomarkers, Tumor/immunology; Blotting, Western; Brain/metabolism; Carrier Proteins/immunology; Case-Control Studies; Creutzfeldt-Jakob Syndrome/pathology; DNA-Binding Proteins/immunology; Female; Frontal Lobe/metabolism; Humans; Immunoenzyme Techniques; Male; Mice; Mice, Inbred BALB C; Peptide Fragments/immunology; Phosphopyruvate Hydratase/immunology; Plasminogen/metabolism; Protein Processing, Post-Translational; Protein-Arginine Deiminases; Recombinant Proteins/genetics; Recombinant Proteins/metabolism; Tumor Suppressor Proteins/immunology