Activation of ATP-sensitive potassium channels as an element of the neuroprotective effects of the Traditional Chinese Medicine MLC901 against oxygen glucose deprivation.

Moha Ou Maati, H; Borsotto, M; Chatelain, F; Widmann, C; Lazdunski, M; Heurteaux, C

Moha Ou Maati, H; Borsotto, M; Chatelain, F; Widmann, C; Lazdunski, M; Heurteaux, C.

Affiliation

Moha Ou Maati H; Institut de Pharmacologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique (CNRS, UMR6097), Université de Nice Sophia Antipolis, 660 Route des Lucioles, 06560 Valbonne, France.

Neuropharmacology ; 63(4): 692-700, 2012 Sep.

Article in En | MEDLINE | ID: mdl-22659084

Subject(s)

Cell Hypoxia/drug effects; Cerebral Cortex/drug effects; Drugs, Chinese Herbal/pharmacology; Glucose/metabolism; KATP Channels/agonists; Neurons/drug effects; Neuroprotective Agents/pharmacology; Animals; COS Cells; Calcium Signaling/drug effects; Cell Line; Cell Survival/drug effects; Cells, Cultured; Cerebral Cortex/cytology; Cerebral Cortex/metabolism; Chlorocebus aethiops; Embryo, Mammalian; KATP Channels/antagonists & inhibitors; KATP Channels/metabolism; Membrane Potentials/drug effects; Membrane Transport Modulators/pharmacology; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins/agonists; Nerve Tissue Proteins/antagonists & inhibitors; Nerve Tissue Proteins/metabolism; Neurons/cytology; Neurons/metabolism; Potassium Channel Blockers/pharmacology; Rats

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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Drugs, Chinese Herbal / Cell Hypoxia / Cerebral Cortex / Neuroprotective Agents / KATP Channels / Glucose / Neurons Type of study: Diagnostic_studies Language: En Journal: Neuropharmacology Year: 2012 Type: Article Affiliation country: France

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