Rosmarinus officinalis L. hydroalcoholic extract, similar to fluoxetine, reverses depressive-like behavior without altering learning deficit in olfactory bulbectomized mice.

Machado, Daniele G; Cunha, Mauricio P; Neis, Vivian B; Balen, Grasiela O; Colla, André R; Grando, Jaine; Brocardo, Patricia S; Bettio, Luis E B; Dalmarco, Juliana B; Rial, Daniel; Prediger, Rui D; Pizzolatti, Moacir G; Rodrigues, Ana Lúcia S

Machado, Daniele G; Cunha, Mauricio P; Neis, Vivian B; Balen, Grasiela O; Colla, André R; Grando, Jaine; Brocardo, Patricia S; Bettio, Luis E B; Dalmarco, Juliana B; Rial, Daniel; Prediger, Rui D; Pizzolatti, Moacir G; Rodrigues, Ana Lúcia S.

Affiliation

Machado DG; Department of Biochemistry, Center of Biological Sciences, Universidade Federal de Santa Catarina, Campus Universitário, Trindade, 88040-900 Florianópolis, SC, Brazil.

J Ethnopharmacol ; 143(1): 158-69, 2012 Aug 30.

Article in En | MEDLINE | ID: mdl-22721880

Subject(s)

Behavior, Animal/drug effects; Depression/drug therapy; Learning Disabilities/metabolism; Learning/drug effects; Phytotherapy; Plant Extracts/therapeutic use; Rosmarinus; Acetylcholinesterase/metabolism; Animals; Antidepressive Agents/pharmacology; Antidepressive Agents/therapeutic use; Blood Glucose/metabolism; Depression/complications; Depression/metabolism; Exploratory Behavior/drug effects; Female; Fluoxetine/pharmacology; Fluoxetine/therapeutic use; Hippocampus/drug effects; Hippocampus/metabolism; Hyperkinesis/drug therapy; Hyperkinesis/etiology; Hyperkinesis/metabolism; Hypoglycemia/drug therapy; Learning Disabilities/drug therapy; Learning Disabilities/etiology; Mice; Mice, Inbred Strains; Olfactory Bulb/surgery; Plant Extracts/pharmacology

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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas / Aromoterapia / Plantas_medicinales Main subject: Behavior, Animal / Plant Extracts / Rosmarinus / Depression / Learning / Learning Disabilities / Phytotherapy Type of study: Etiology_studies Language: En Journal: J Ethnopharmacol Year: 2012 Type: Article Affiliation country: Brazil

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