Fast mouse PK (Fast PK): a rapid screening method to increase pharmacokinetic throughput in pre-clinical drug discovery.

Reddy, Jitendar; Madishetti, Sreedhar; Vachaspati, Prakash R

Reddy, Jitendar; Madishetti, Sreedhar; Vachaspati, Prakash R.

Affiliation

Reddy J; DMPK, Infection Innovative Medicines, AstraZeneca India Pvt. Ltd., Kirloskar Business Park, Hebbal, Bangalore 560 024, India.

Eur J Pharm Sci ; 47(2): 444-50, 2012 Sep 29.

Article in En | MEDLINE | ID: mdl-22789493

Subject(s)

Drug Evaluation, Preclinical/methods; Pharmacokinetics; Administration, Intravenous; Administration, Oral; Animals; Male; Mice; Mice, Inbred BALB C; Pharmaceutical Preparations/metabolism; Rifampin/administration & dosage; Rifampin/blood; Rifampin/pharmacokinetics

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Full text: 1 Database: MEDLINE Main subject: Pharmacokinetics / Drug Evaluation, Preclinical Type of study: Diagnostic_studies / Screening_studies Language: En Journal: Eur J Pharm Sci Year: 2012 Type: Article Affiliation country: India

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