Therapeutic potential of mipomersen in the management of familial hypercholesterolaemia.

Gelsinger, Carmen; Steinhagen-Thiessen, Elisabeth; Kassner, Ursula

Gelsinger, Carmen; Steinhagen-Thiessen, Elisabeth; Kassner, Ursula.

Affiliation

Gelsinger C; Lipid Clinic at the Interdisciplinary Metabolism Center, Charité-Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany.

Drugs ; 72(11): 1445-55, 2012 Jul 30.

Article in En | MEDLINE | ID: mdl-22799743

Subject(s)

Anticholesteremic Agents/therapeutic use; Hyperlipoproteinemia Type II/drug therapy; Oligonucleotides/therapeutic use; Animals; Anticholesteremic Agents/adverse effects; Apolipoprotein B-100/antagonists & inhibitors; Apolipoprotein B-100/blood; Apolipoprotein B-100/metabolism; Cholesterol, LDL/blood; Cholesterol, LDL/metabolism; Cholesterol, VLDL/blood; Cholesterol, VLDL/metabolism; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Double-Blind Method; Drug Evaluation, Preclinical; Humans; Hyperlipoproteinemia Type II/blood; Hyperlipoproteinemia Type II/metabolism; Lipoprotein(a)/blood; Lipoprotein(a)/metabolism; Oligonucleotides/adverse effects; Randomized Controlled Trials as Topic; Triglycerides/blood; Triglycerides/metabolism

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Full text: 1 Database: MEDLINE Main subject: Oligonucleotides / Hyperlipoproteinemia Type II / Anticholesteremic Agents Type of study: Clinical_trials Language: En Journal: Drugs Year: 2012 Type: Article Affiliation country: Germany

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