Preclinical evaluation of VB6-845: an anti-EpCAM immunotoxin with reduced immunogenic potential.

Entwistle, Joycelyn; Brown, Jennifer G; Chooniedass, Shilpa; Cizeau, Jeannick; MacDonald, Glen C

Entwistle, Joycelyn; Brown, Jennifer G; Chooniedass, Shilpa; Cizeau, Jeannick; MacDonald, Glen C.

Affiliation

Entwistle J; Department of Research, Viventia Biotechnologies, Inc., Winnipeg, Manitoba, Canada. jentwistle@viventia.com

Cancer Biother Radiopharm ; 27(9): 582-92, 2012 Nov.

Article in En | MEDLINE | ID: mdl-22856424

Subject(s)

Immunotoxins/pharmacology; Recombinant Fusion Proteins/pharmacology; Animals; Antigens, Neoplasm/immunology; Cell Adhesion Molecules/immunology; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Epithelial Cell Adhesion Molecule; Female; Humans; Immunotherapy/methods; Macaca fascicularis; Male; Mice; Rats; Rats, Sprague-Dawley; Xenograft Model Antitumor Assays

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Full text: 1 Database: MEDLINE Main subject: Recombinant Fusion Proteins / Immunotoxins Language: En Journal: Cancer Biother Radiopharm Year: 2012 Type: Article Affiliation country: Canada

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