The cellular level of histone H3 lysine 4 dimethylation correlates with response to adjuvant gemcitabine in Japanese pancreatic cancer patients treated with surgery.

Watanabe, T; Morinaga, S; Akaike, M; Numata, M; Tamagawa, H; Yamamoto, N; Shiozawa, M; Ohkawa, S; Kameda, Y; Nakamura, Y; Miyagi, Y

Watanabe, T; Morinaga, S; Akaike, M; Numata, M; Tamagawa, H; Yamamoto, N; Shiozawa, M; Ohkawa, S; Kameda, Y; Nakamura, Y; Miyagi, Y.

Affiliation

Watanabe T; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, 1-1-2 Nakao, Asahi-ku, Yokohama, Kanagawa-ken 241-0815, Japan. twgiraud@gmail.com

Eur J Surg Oncol ; 38(11): 1051-7, 2012 Nov.

Article in En | MEDLINE | ID: mdl-22959167

Subject(s)

Antimetabolites, Antineoplastic/therapeutic use; Deoxycytidine/analogs & derivatives; Histones/metabolism; Pancreatic Neoplasms/surgery; Adult; Aged; Aged, 80 and over; Chemotherapy, Adjuvant; Deoxycytidine/therapeutic use; Disease-Free Survival; Female; Humans; Immunohistochemistry; Lysine/metabolism; Male; Methylation; Middle Aged; Pancreatic Neoplasms/metabolism; Gemcitabine

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Full text: 1 Database: MEDLINE Main subject: Pancreatic Neoplasms / Histones / Deoxycytidine / Antimetabolites, Antineoplastic Type of study: Prognostic_studies Language: En Journal: Eur J Surg Oncol Year: 2012 Type: Article Affiliation country: Japan

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