Apoptosis of K562 leukemia cells by Abnobaviscum F®, a European mistletoe             extract.

Park, Yu-Kyoung; Do, Young Rok; Jang, Byeong-Churl

Apoptosis of K562 leukemia cells by Abnobaviscum F®, a European mistletoe extract.

Park, Yu-Kyoung; Do, Young Rok; Jang, Byeong-Churl.

Affiliation

Park YK; Department of Medical Genetic Engineering, School of Medicine, Keimyung University, Dalseo-Gu, Daegu 704-701, Republic of Korea.

Oncol Rep ; 28(6): 2227-32, 2012 Dec.

Article in En | MEDLINE | ID: mdl-22972372

Subject(s)

Apoptosis/drug effects; Leukemia, Lymphoid/pathology; Leukemia, Myeloid/metabolism; Plant Extracts/pharmacology; Viscum album/chemistry; Amino Acid Chloromethyl Ketones/pharmacology; Animals; Anthracenes/pharmacology; Caspase 9/biosynthesis; Caspase 9/metabolism; Cell Line, Tumor; DNA Fragmentation/drug effects; Down-Regulation/drug effects; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress/drug effects; Eukaryotic Initiation Factor-2/metabolism; Extracellular Signal-Regulated MAP Kinases/biosynthesis; Glutathione/metabolism; Glutathione/pharmacology; Heat-Shock Proteins/biosynthesis; Humans; JNK Mitogen-Activated Protein Kinases/metabolism; K562 Cells; Leukemia, Lymphoid/metabolism; Mice; Myeloid Cell Leukemia Sequence 1 Protein; Phosphorylation/drug effects; Plasmacytoma/metabolism; Proto-Oncogene Proteins c-akt/metabolism; Proto-Oncogene Proteins c-bcl-2/biosynthesis; Receptors, TNF-Related Apoptosis-Inducing Ligand/biosynthesis; Transcription Factor CHOP/biosynthesis; p38 Mitogen-Activated Protein Kinases/metabolism

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Full text: 1 Database: MEDLINE Main subject: Plant Extracts / Leukemia, Lymphoid / Leukemia, Myeloid / Apoptosis / Viscum album Language: En Journal: Oncol Rep Year: 2012 Type: Article

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