A nanostructured liquid crystalline formulation of 20(S)-protopanaxadiol with improved oral absorption.

Jin, Xin; Zhang, Zhen-Hai; Li, Song-Lin; Sun, E; Tan, Xiao-Bin; Song, Jie; Jia, Xiao-Bin

Jin, Xin; Zhang, Zhen-Hai; Li, Song-Lin; Sun, E; Tan, Xiao-Bin; Song, Jie; Jia, Xiao-Bin.

Affiliation

Jin X; Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing, PR China.

Fitoterapia ; 84: 64-71, 2013 Jan.

Article in En | MEDLINE | ID: mdl-23006538

Subject(s)

Antineoplastic Agents, Phytogenic/pharmacokinetics; Sapogenins/pharmacokinetics; Administration, Oral; Animals; Antineoplastic Agents, Phytogenic/administration & dosage; Antineoplastic Agents, Phytogenic/chemistry; Area Under Curve; Biological Availability; Caco-2 Cells; Half-Life; Humans; Intestinal Mucosa/metabolism; Liquid Crystals; Male; Molecular Structure; Nanostructures; Perfusion; Rats; Rats, Sprague-Dawley; Sapogenins/administration & dosage; Sapogenins/chemistry

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Full text: 1 Database: MEDLINE Main subject: Sapogenins / Antineoplastic Agents, Phytogenic Type of study: Prognostic_studies Language: En Journal: Fitoterapia Year: 2013 Type: Article

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