Gomisin N in the herbal drug gomishi (Schisandra chinensis) suppresses inducible nitric oxide synthase gene via C/EBPß and NF-&#954;B in rat hepatocytes.

Takimoto, Yuna; Qian, Hai-Yan; Yoshigai, Emi; Okumura, Tadayoshi; Ikeya, Yukinobu; Nishizawa, Mikio

Gomisin N in the herbal drug gomishi (Schisandra chinensis) suppresses inducible nitric oxide synthase gene via C/EBPß and NF-κB in rat hepatocytes.

Takimoto, Yuna; Qian, Hai-Yan; Yoshigai, Emi; Okumura, Tadayoshi; Ikeya, Yukinobu; Nishizawa, Mikio.

Affiliation

Takimoto Y; Department of Biomedical Sciences, College of Life Sciences, Ritsumeikan University, Kusatsu, Shiga, Japan.

Nitric Oxide ; 28: 47-56, 2013 Jan 15.

Article in En | MEDLINE | ID: mdl-23085209

Subject(s)

CCAAT-Enhancer-Binding Protein-beta/metabolism; Hepatocytes/drug effects; Lignans/pharmacology; NF-kappa B/metabolism; Nitric Oxide Synthase Type II/genetics; Polycyclic Compounds/pharmacology; Schisandra/chemistry; Animals; Cells, Cultured; Cyclooctanes/chemistry; Cyclooctanes/pharmacology; Dose-Response Relationship, Drug; Hepatocytes/enzymology; Hepatocytes/metabolism; Lignans/chemistry; Male; Nitric Oxide/biosynthesis; Nitric Oxide Synthase Type II/biosynthesis; Polycyclic Compounds/chemistry; Rats; Rats, Wistar; Structure-Activity Relationship

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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_japonesa Main subject: Polycyclic Compounds / NF-kappa B / Lignans / Hepatocytes / CCAAT-Enhancer-Binding Protein-beta / Schisandra / Nitric Oxide Synthase Type II Language: En Journal: Nitric Oxide Year: 2013 Type: Article Affiliation country: Japan

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