Intermittent hypoxia and stem cell implants preserve breathing capacity in a rodent model of amyotrophic lateral sclerosis.

Nichols, Nicole L; Gowing, Genevieve; Satriotomo, Irawan; Nashold, Lisa J; Dale, Erica A; Suzuki, Masatoshi; Avalos, Pablo; Mulcrone, Patrick L; McHugh, Jacalyn; Svendsen, Clive N; Mitchell, Gordon S

Nichols, Nicole L; Gowing, Genevieve; Satriotomo, Irawan; Nashold, Lisa J; Dale, Erica A; Suzuki, Masatoshi; Avalos, Pablo; Mulcrone, Patrick L; McHugh, Jacalyn; Svendsen, Clive N; Mitchell, Gordon S.

Affiliation

Nichols NL; Department of Comparative Biosciences, University of Wisconsin, Madison, WI 53706, USA.

Am J Respir Crit Care Med ; 187(5): 535-42, 2013 Mar 01.

Article in En | MEDLINE | ID: mdl-23220913

Subject(s)

Amyotrophic Lateral Sclerosis/therapy; Respiratory Insufficiency/prevention & control; Respiratory Therapy/methods; Stem Cell Transplantation; Animals; Brain-Derived Neurotrophic Factor/biosynthesis; Glial Cell Line-Derived Neurotrophic Factor/metabolism; Hypoxia; Inspiratory Capacity; Male; Motor Neurons/metabolism; Phrenic Nerve/metabolism; Phrenic Nerve/physiopathology; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Superoxide Dismutase

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Full text: 1 Database: MEDLINE Main subject: Respiratory Insufficiency / Respiratory Therapy / Stem Cell Transplantation / Amyotrophic Lateral Sclerosis Type of study: Evaluation_studies / Prognostic_studies Language: En Journal: Am J Respir Crit Care Med Year: 2013 Type: Article Affiliation country: United States

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