Identification of a 3-aminoimidazo[1,2-a]pyridine inhibitor of HIV-1 reverse transcriptase.

Elleder, Daniel; Baiga, Thomas J; Russell, Rebecca L; Naughton, John A; Hughes, Stephen H; Noel, Joseph P; Young, John A T

Elleder, Daniel; Baiga, Thomas J; Russell, Rebecca L; Naughton, John A; Hughes, Stephen H; Noel, Joseph P; Young, John A T.

Affiliation

Elleder D; The Salk Institute for Biological Studies, Nomis Center for Immunobiology and Microbial Pathogenesis, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

Virol J ; 9: 305, 2012 Dec 11.

Article in En | MEDLINE | ID: mdl-23231773

Subject(s)

Anti-HIV Agents/pharmacology; HIV Infections/virology; HIV Reverse Transcriptase/antagonists & inhibitors; HIV-1/drug effects; Imidazoles/pharmacology; Pyrazines/pharmacology; Reverse Transcriptase Inhibitors/pharmacology; Anti-HIV Agents/chemistry; Drug Evaluation, Preclinical; HIV Infections/drug therapy; HIV Reverse Transcriptase/metabolism; HIV-1/enzymology; HIV-1/physiology; Humans; Imidazoles/chemistry; Pyrazines/chemistry; Reverse Transcriptase Inhibitors/chemistry; Small Molecule Libraries/pharmacology

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Full text: 1 Database: MEDLINE Main subject: Pyrazines / HIV Infections / HIV-1 / Reverse Transcriptase Inhibitors / Anti-HIV Agents / HIV Reverse Transcriptase / Imidazoles Type of study: Diagnostic_studies Language: En Journal: Virol J Year: 2012 Type: Article Affiliation country: United States

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