Paraptosis and NF-&#954;B activation are associated with protopanaxadiol-induced cancer chemoprevention.

Wang, Chong-Zhi; Li, Binghui; Wen, Xiao-Dong; Zhang, Zhiyu; Yu, Chunhao; Calway, Tyler D; He, Tong-Chuan; Du, Wei; Yuan, Chun-Su

Paraptosis and NF-κB activation are associated with protopanaxadiol-induced cancer chemoprevention.

Wang, Chong-Zhi; Li, Binghui; Wen, Xiao-Dong; Zhang, Zhiyu; Yu, Chunhao; Calway, Tyler D; He, Tong-Chuan; Du, Wei; Yuan, Chun-Su.

Affiliation

Wang CZ; Tang Center for Herbal Medicine Research, University of Chicago, Chicago, IL, USA.

BMC Complement Altern Med ; 13: 2, 2013 Jan 03.

Article in En | MEDLINE | ID: mdl-23281928

Subject(s)

Anticarcinogenic Agents/pharmacology; Cell Death/drug effects; Colorectal Neoplasms/prevention & control; NF-kappa B/metabolism; Panax/chemistry; Phytotherapy; Sapogenins/pharmacology; Anticarcinogenic Agents/therapeutic use; Antineoplastic Agents, Phytogenic/pharmacology; Antineoplastic Agents, Phytogenic/therapeutic use; Chemoprevention; Colorectal Neoplasms/metabolism; HCT116 Cells; Heterocyclic Compounds, 3-Ring/pharmacology; Humans; Mitochondria/drug effects; Plant Extracts/pharmacology; Plant Extracts/therapeutic use; Pyridines/pharmacology; Reactive Oxygen Species/metabolism; Sapogenins/therapeutic use; Signal Transduction; Vacuoles/drug effects

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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas / Plantas_medicinales Main subject: Sapogenins / Colorectal Neoplasms / NF-kappa B / Cell Death / Anticarcinogenic Agents / Panax / Phytotherapy Type of study: Risk_factors_studies Language: En Journal: BMC Complement Altern Med Year: 2013 Type: Article Affiliation country: United States

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