Alkamides from Echinacea angustifolia Interact with P-glycoprotein of primary brain capillary endothelial cells isolated from porcine brain blood vessels.

Mahringer, Anne; Ardjomand-Woelkart, Karin; Bauer, Rudolf; Fricker, Gert; Efferth, Thomas

Mahringer, Anne; Ardjomand-Woelkart, Karin; Bauer, Rudolf; Fricker, Gert; Efferth, Thomas.

Affiliation

Mahringer A; Institute of Pharmacy and Molecular Biotechnology, Department of Pharmaceutical Technology and Pharmacology, University of Heidelberg, Heidelberg, Germany.

Planta Med ; 79(3-4): 214-8, 2013 Mar.

Article in En | MEDLINE | ID: mdl-23322561

Subject(s)

ATP Binding Cassette Transporter, Subfamily B/metabolism; Echinacea/chemistry; Endothelial Cells/drug effects; Endothelial Cells/metabolism; Polyunsaturated Alkamides/pharmacology; ATP Binding Cassette Transporter, Subfamily B/antagonists & inhibitors; Animals; Biological Transport/drug effects; Blood-Brain Barrier/drug effects; Brain/blood supply; Cells, Cultured; Dose-Response Relationship, Drug; Flow Cytometry/methods; Fluoresceins/metabolism; Molecular Structure; Polyunsaturated Alkamides/chemistry; Polyunsaturated Alkamides/isolation & purification; Swine

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Full text: 1 Database: MEDLINE Main subject: ATP Binding Cassette Transporter, Subfamily B / Echinacea / Endothelial Cells / Polyunsaturated Alkamides Language: En Journal: Planta Med Year: 2013 Type: Article Affiliation country: Germany

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