A novel approach to enhancing ganoderic acid production by Ganoderma lucidum using apoptosis induction.

You, Bang-Jau; Lee, Miin-Huey; Tien, Ni; Lee, Meng-Shiou; Hsieh, Hui-Chuan; Tseng, Lin-Hsien; Chung, Yu-Lin; Lee, Hong-Zin

You, Bang-Jau; Lee, Miin-Huey; Tien, Ni; Lee, Meng-Shiou; Hsieh, Hui-Chuan; Tseng, Lin-Hsien; Chung, Yu-Lin; Lee, Hong-Zin.

Affiliation

You BJ; Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung, Taiwan. bangjau@mail.cmu.edu.tw

PLoS One ; 8(1): e53616, 2013.

Article in En | MEDLINE | ID: mdl-23326470

Subject(s)

Apoptosis; Cell Culture Techniques/methods; Reishi/cytology; Reishi/metabolism; Triterpenes/metabolism; Apoptosis/drug effects; Aspirin/pharmacology; Biomass; Cell Nucleus/drug effects; Cell Nucleus/metabolism; DNA Fragmentation/drug effects; Farnesyl-Diphosphate Farnesyltransferase/genetics; Farnesyl-Diphosphate Farnesyltransferase/metabolism; Gene Expression Regulation, Fungal/drug effects; Intramolecular Transferases/genetics; Intramolecular Transferases/metabolism; Mitogen-Activated Protein Kinases/metabolism; Phosphorylation/drug effects; RNA, Messenger/genetics; RNA, Messenger/metabolism; Reactive Oxygen Species/metabolism; Reishi/drug effects; Reishi/genetics; Time Factors; Transcription, Genetic/drug effects

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Full text: 1 Database: MEDLINE Main subject: Triterpenes / Apoptosis / Cell Culture Techniques / Reishi Type of study: Prognostic_studies Language: En Journal: PLoS One Year: 2013 Type: Article Affiliation country: Taiwan

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