Dose-dependent effects of nicotine on proliferation and differentiation of human bone marrow stromal cells and the antagonistic action of vitamin C.

Shen, Yue; Liu, Hai-xiao; Ying, Xiao-zhou; Yang, Shi-zhou; Nie, Peng-fei; Cheng, Shao-wen; Wang, Wei; Cheng, Xiao-jie; Peng, Lei; Xu, Hua-zi

Shen, Yue; Liu, Hai-xiao; Ying, Xiao-zhou; Yang, Shi-zhou; Nie, Peng-fei; Cheng, Shao-wen; Wang, Wei; Cheng, Xiao-jie; Peng, Lei; Xu, Hua-zi.

Affiliation

Shen Y; Department of Orthopaedic Surgery, The Second Affiliated Hospital of Wenzhou Medical College, Wenzhou, Zhejiang Province 325000, People's Republic of China.

J Cell Biochem ; 114(8): 1720-8, 2013 Aug.

Article in En | MEDLINE | ID: mdl-23386463

Subject(s)

Antioxidants/pharmacology; Ascorbic Acid/pharmacology; Bone Marrow Cells/metabolism; Cell Differentiation/drug effects; Cell Proliferation/drug effects; Ganglionic Stimulants/pharmacology; Nicotine/pharmacology; Osteogenesis/drug effects; Adult; Aged; Ascorbic Acid/antagonists & inhibitors; Bone Marrow Cells/cytology; Bone Morphogenetic Protein 2/biosynthesis; Cells, Cultured; Dose-Response Relationship, Drug; Drug Antagonism; Female; Ganglionic Stimulants/antagonists & inhibitors; Gene Expression Regulation/drug effects; Humans; Male; Middle Aged; Nicotine/antagonists & inhibitors; Stromal Cells/cytology; Stromal Cells/metabolism

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Full text: 1 Database: MEDLINE Main subject: Osteogenesis / Ascorbic Acid / Bone Marrow Cells / Cell Differentiation / Cell Proliferation / Ganglionic Stimulants / Nicotine / Antioxidants Language: En Journal: J Cell Biochem Year: 2013 Type: Article

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