Warfarin accelerates ectopic mineralization in Abcc6(-/-) mice: clinical relevance to pseudoxanthoma elasticum.

Li, Qiaoli; Guo, Haitao; Chou, David W; Harrington, Dominic J; Schurgers, Leon J; Terry, Sharon F; Uitto, Jouni

Li, Qiaoli; Guo, Haitao; Chou, David W; Harrington, Dominic J; Schurgers, Leon J; Terry, Sharon F; Uitto, Jouni.

Affiliation

Li Q; Department of Dermatology and Cutaneous Biology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

Am J Pathol ; 182(4): 1139-50, 2013 Apr.

Article in En | MEDLINE | ID: mdl-23415960

Subject(s)

ATP-Binding Cassette Transporters/deficiency; Calcification, Physiologic/drug effects; Pseudoxanthoma Elasticum/pathology; Warfarin/adverse effects; ATP-Binding Cassette Transporters/metabolism; Animals; Calcium/blood; Calcium-Binding Proteins/metabolism; Dermis/diagnostic imaging; Dermis/drug effects; Dermis/pathology; Diet; Dietary Supplements; Disease Models, Animal; Extracellular Matrix Proteins/metabolism; Humans; Magnesium/metabolism; Mice; Minerals/metabolism; Multidrug Resistance-Associated Proteins; Organ Specificity/drug effects; Phosphates/metabolism; Phosphorus/blood; Pseudoxanthoma Elasticum/blood; Pseudoxanthoma Elasticum/diagnostic imaging; Vitamin K/blood; Warfarin/blood; X-Ray Microtomography; Matrix Gla Protein

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Full text: 1 Database: MEDLINE Main subject: Pseudoxanthoma Elasticum / Warfarin / Calcification, Physiologic / ATP-Binding Cassette Transporters Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: Am J Pathol Year: 2013 Type: Article Affiliation country: United States

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