New transient receptor potential vanilloid subfamily member 1 positron emission tomography radioligands: synthesis, radiolabeling, and preclinical evaluation.

van Veghel, Daisy; Cleynhens, Jan; Pearce, Larry V; DeAndrea-Lazarus, Ian A; Blumberg, Peter M; Van Laere, Koen; Verbruggen, Alfons; Bormans, Guy

van Veghel, Daisy; Cleynhens, Jan; Pearce, Larry V; DeAndrea-Lazarus, Ian A; Blumberg, Peter M; Van Laere, Koen; Verbruggen, Alfons; Bormans, Guy.

Affiliation

van Veghel D; Laboratory for Radiopharmacy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Campus Gasthuisberg O&N2, Herestraat 49 box 821, 3000 Leuven, Belgium.

ACS Chem Neurosci ; 4(4): 624-34, 2013 Apr 17.

Article in En | MEDLINE | ID: mdl-23421633

Subject(s)

Carbon Radioisotopes/metabolism; Fluorine Radioisotopes/metabolism; Positron-Emission Tomography/methods; Radioligand Assay/methods; TRPV Cation Channels/metabolism; Animals; Carbon Radioisotopes/chemistry; Drug Evaluation, Preclinical/methods; Fluorine Radioisotopes/chemistry; Humans; Male; Mice; Protein Binding

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Full text: 1 Database: MEDLINE Main subject: Radioligand Assay / Carbon Radioisotopes / Fluorine Radioisotopes / Positron-Emission Tomography / TRPV Cation Channels Language: En Journal: ACS Chem Neurosci Year: 2013 Type: Article Affiliation country: Belgium

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