Nephroprotective effect of calcium channel blockers against toxicity of lead exposure in mice.

Zhang, Jianping; Cao, Hua; Zhang, Ying; Zhang, Yuanyuan; Ma, Juanjuan; Wang, Jiangyan; Gao, Yonggang; Zhang, Xuan; Zhang, Fenghua; Chu, Li

Zhang, Jianping; Cao, Hua; Zhang, Ying; Zhang, Yuanyuan; Ma, Juanjuan; Wang, Jiangyan; Gao, Yonggang; Zhang, Xuan; Zhang, Fenghua; Chu, Li.

Affiliation

Zhang J; Department of Pharmacology, School of Basic Medicine, Hebei Medical University, 326, Xinshi South Road, Shijiazhuang 050091, Hebei, China.

Toxicol Lett ; 218(3): 273-80, 2013 Apr 26.

Article in En | MEDLINE | ID: mdl-23428833

Subject(s)

Calcium Channel Blockers/pharmacology; Kidney Diseases/prevention & control; Kidney/drug effects; Lead Poisoning/drug therapy; Nimodipine/pharmacology; Verapamil/pharmacology; Animals; Apoptosis/drug effects; Blood Urea Nitrogen; Body Weight/drug effects; Creatinine/blood; Cytoprotection; Disease Models, Animal; Glutathione Peroxidase/metabolism; Kidney/metabolism; Kidney/pathology; Kidney Diseases/etiology; Kidney Diseases/metabolism; Kidney Diseases/pathology; Lead Poisoning/complications; Lead Poisoning/metabolism; Lead Poisoning/pathology; Lipid Peroxidation; Male; Malondialdehyde/metabolism; Mice; Organ Size/drug effects; Organometallic Compounds; Superoxide Dismutase/metabolism

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Full text: 1 Database: MEDLINE Main subject: Calcium Channel Blockers / Verapamil / Nimodipine / Kidney / Kidney Diseases / Lead Poisoning Type of study: Etiology_studies / Prognostic_studies Language: En Journal: Toxicol Lett Year: 2013 Type: Article Affiliation country: China

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