Polysaccharide from Fuzi likely protects against starvation-induced cytotoxicity in H9c2 cells by increasing autophagy through activation of the AMPK/mTOR pathway.

Liao, Li-Zhen; Chen, Yan-Ling; Lu, Li-He; Zhao, Yong-Hua; Guo, Hua-Lei; Wu, Wei-Kang

Liao, Li-Zhen; Chen, Yan-Ling; Lu, Li-He; Zhao, Yong-Hua; Guo, Hua-Lei; Wu, Wei-Kang.

Affiliation

Liao LZ; Department of Pathophysiology, Zhongshan Medical School, Sun Yat-Sen University, Guangzhou, Guangdong 510080, P. R. China.

Am J Chin Med ; 41(2): 353-67, 2013.

Article in En | MEDLINE | ID: mdl-23548125

Subject(s)

AMP-Activated Protein Kinases/metabolism; Aconitum/chemistry; Autophagy/drug effects; Drugs, Chinese Herbal/pharmacology; Myocytes, Cardiac/cytology; Polysaccharides/pharmacology; Protective Agents/pharmacology; Starvation/complications; TOR Serine-Threonine Kinases/metabolism; Animals; Apoptosis/drug effects; Cell Line, Tumor; Myocytes, Cardiac/drug effects; Myocytes, Cardiac/metabolism; Rats; Signal Transduction/drug effects

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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Polysaccharides / Autophagy / Starvation / Drugs, Chinese Herbal / Protective Agents / Myocytes, Cardiac / Aconitum / AMP-Activated Protein Kinases / TOR Serine-Threonine Kinases Language: En Journal: Am J Chin Med Year: 2013 Type: Article

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