Effect of N-acetyl cysteine (NAC), an organosulfur compound from Allium plants, on experimentally induced hepatic prefibrogenic events in Wistar rat.

Nissar, Ashraf U; Farrukh, Mufti R; Kaiser, Peerzada J; Rafiq, Rather A; Afnan, Quadri; Bhushan, Shashi; Adil, Hassan S; Subhash, Bhardjwaj C; Tasduq, Sheikh A

Nissar, Ashraf U; Farrukh, Mufti R; Kaiser, Peerzada J; Rafiq, Rather A; Afnan, Quadri; Bhushan, Shashi; Adil, Hassan S; Subhash, Bhardjwaj C; Tasduq, Sheikh A.

Affiliation

Nissar AU; PK-PD and Toxicology Division, Indian Institute of Integrative Medicine, Council of Scientific and Industrial Research, Jammu-Tawi, Jammu and Kashmir, India.

Phytomedicine ; 20(10): 828-33, 2013 Jul 15.

Article in En | MEDLINE | ID: mdl-23578993

Subject(s)

Acetylcysteine/therapeutic use; Allium; Liver Cirrhosis/prevention & control; Oxidative Stress/drug effects; Sulfur/administration & dosage; Acetylcysteine/pharmacology; Animals; Carbon Tetrachloride/administration & dosage; Disease Models, Animal; Liver Cirrhosis/chemically induced; Liver Cirrhosis/pathology; Male; Phytotherapy; Rats; Rats, Wistar; Thioacetamide/administration & dosage

Key words

ALP; ALT; AST; Alanine aminotransferase; Alkaline phosphatase; Aspartate aminotransferase; CAT; CCl(4); CYP2E1; Carbon tetrachloride; Catalase; Cytochrome P450 2E1; Fibrosis; GPx; GSH; Glutathione; Glutathione peroxidase; LPO; Lipidperoxidation; Liver; MDA; Malonaldehyde; N-acetyl cysteine from Allium plants; N-acetylcysteine; NAC; OS; Oxidative stress; TAA; Thioacetamide; Wistar rat

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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas Main subject: Acetylcysteine / Sulfur / Allium / Oxidative Stress / Liver Cirrhosis Type of study: Prognostic_studies Language: En Journal: Phytomedicine Year: 2013 Type: Article Affiliation country: India

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