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Phenotypic and genotypic characterization of acyclovir-resistant corneal HSV-1 isolates from immunocompetent patients with recurrent herpetic keratitis.
Burrel, Sonia; Boutolleau, David; Azar, Georges; Doan, Serge; Deback, Claire; Cochereau, Isabelle; Agut, Henri; Gabison, Eric E.
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  • Burrel S; UPMC Univ Paris 06, ER1 DETIV, F-75013 Paris, France.
J Clin Virol ; 58(1): 321-4, 2013 Sep.
Article in En | MEDLINE | ID: mdl-23731845
ABSTRACT
Herpes simplex virus type 1 (HSV-1) is a leading cause of corneal blindness. Acyclovir (ACV) constitutes the standard treatment of HSV infections including herpetic keratitis (HK). HSV resistance to ACV is mainly described in immunocompromised patients. We describe two cases of ACV-resistant corneal HSV-1 in immunocompetent individuals with recurrent HK.
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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Plantas_medicinales Main subject: Antiviral Agents / Acyclovir / Keratitis, Herpetic / Herpesvirus 1, Human / Drug Resistance, Viral Language: En Journal: J Clin Virol Year: 2013 Type: Article Affiliation country: France
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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Plantas_medicinales Main subject: Antiviral Agents / Acyclovir / Keratitis, Herpetic / Herpesvirus 1, Human / Drug Resistance, Viral Language: En Journal: J Clin Virol Year: 2013 Type: Article Affiliation country: France