Melatonin synthesis in human colostrum mononuclear cells enhances dectin-1-mediated phagocytosis by mononuclear cells.

Pires-Lapa, Marco A; Tamura, Eduardo K; Salustiano, Eugenia M A; Markus, Regina P

Pires-Lapa, Marco A; Tamura, Eduardo K; Salustiano, Eugenia M A; Markus, Regina P.

Affiliation

Pires-Lapa MA; Laboratory of Chronopharmacology, Institute of Bioscience, University of São Paulo, São Paulo, SP, Brazil.

J Pineal Res ; 55(3): 240-6, 2013 Oct.

Article in En | MEDLINE | ID: mdl-23745599

Subject(s)

Colostrum/metabolism; Lectins, C-Type/metabolism; Leukocytes, Mononuclear/metabolism; Melatonin/biosynthesis; Phagocytosis/physiology; Adolescent; Adult; Animals; Cell Line; Colostrum/cytology; DNA-Binding Proteins/metabolism; Female; Humans; Infant, Newborn; Leukocytes, Mononuclear/cytology; Melatonin/antagonists & inhibitors; Mice; Nuclear Proteins/metabolism; Phagocytosis/drug effects; Proto-Oncogene Proteins c-rel; Tetrahydronaphthalenes/pharmacology; Transcription Factor RelA/metabolism; Tryptamines/pharmacology

Key words

dectin-1; human colostrum; melatonin; mononuclear cells; nuclear factor kappa B (NF-κB); phagocytosis; zymosan

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Full text: 1 Database: MEDLINE Main subject: Phagocytosis / Leukocytes, Mononuclear / Colostrum / Lectins, C-Type / Melatonin Language: En Journal: J Pineal Res Year: 2013 Type: Article Affiliation country: Brazil

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