Two immunosuppressive compounds from the mushroom Rubinoboletus ballouii using human peripheral blood mononuclear cells by bioactivity-guided fractionation.

Li, Long-Fei; Chan, Ben Chung-Lap; Yue, Grace Gar-Lee; Lau, Clara Bik-San; Han, Quan-Bin; Leung, Ping-Chung; Liu, Ji-Kai; Fung, Kwok-Pui

Li, Long-Fei; Chan, Ben Chung-Lap; Yue, Grace Gar-Lee; Lau, Clara Bik-San; Han, Quan-Bin; Leung, Ping-Chung; Liu, Ji-Kai; Fung, Kwok-Pui.

Affiliation

Li LF; Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, N. T., Hong Kong SAR, China; State Key Laboratory of Phytochemistry and Plant Resources in West China (CUHK), The Chinese University of Hong Kong, Shatin, N. T., Hong Kong SAR, China.

Phytomedicine ; 20(13): 1196-202, 2013 Oct 15.

Article in En | MEDLINE | ID: mdl-23830817

Subject(s)

Agaricales/chemistry; Catechols/isolation & purification; Cell Extracts/isolation & purification; Cytokines/drug effects; Immunosuppressive Agents/isolation & purification; Ribonucleosides/isolation & purification; Triazines/isolation & purification; Biological Assay; Catechols/chemistry; Catechols/pharmacology; Cell Cycle/drug effects; Cell Extracts/chemistry; Cell Extracts/pharmacology; Chemical Fractionation; Cytokines/metabolism; Humans; Immunosuppressive Agents/chemistry; Immunosuppressive Agents/pharmacology; Leukocytes, Mononuclear/drug effects; Leukocytes, Mononuclear/metabolism; Molecular Structure; Ribonucleosides/chemistry; Ribonucleosides/pharmacology; Triazines/chemistry; Triazines/pharmacology

Key words

1-ribofuranosyl-s-triazin-2(1H)-one; Pistillarin; Rubinoboletus ballouii; bioassay-guided fractionation; peripheral blood mononuclear cells (PBMCs)

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Full text: 1 Database: MEDLINE Main subject: Ribonucleosides / Triazines / Catechols / Cell Extracts / Cytokines / Agaricales / Immunosuppressive Agents Language: En Journal: Phytomedicine Year: 2013 Type: Article Affiliation country: China

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