Mistletoe lectin has a shiga toxin-like structure and should be combined with other Toll-like receptor ligands in cancer therapy.

Maletzki, Claudia; Linnebacher, Michael; Savai, Rajkumar; Hobohm, Uwe

Maletzki, Claudia; Linnebacher, Michael; Savai, Rajkumar; Hobohm, Uwe.

Affiliation

Maletzki C; University of Rostock, Rostock, Germany.

Cancer Immunol Immunother ; 62(8): 1283-92, 2013 Aug.

Article in En | MEDLINE | ID: mdl-23832140

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Mistletoe/metabolism; Pancreatic Neoplasms/drug therapy; Plant Lectins/chemistry; Toll-Like Receptors/agonists; Animals; Cell Line, Tumor; Flagellin/administration & dosage; Humans; Imidazoles/administration & dosage; Lipopolysaccharides/administration & dosage; Mice; Mice, Inbred C57BL; Models, Molecular; Neoplasms, Experimental/drug therapy; Pancreatic Neoplasms/pathology; Phytotherapy; Plant Lectins/administration & dosage; Protein Conformation; Shiga Toxin/chemistry; Time Factors; Treatment Outcome; Tumor Burden/drug effects

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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas / Plantas_medicinales Main subject: Pancreatic Neoplasms / Mistletoe / Antineoplastic Combined Chemotherapy Protocols / Plant Lectins / Toll-Like Receptors Type of study: Prognostic_studies Language: En Journal: Cancer Immunol Immunother Year: 2013 Type: Article Affiliation country: Germany

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