Antivenom activity of triterpenoid (C34H68O2) from Leucas aspera Linn. against Naja naja naja venom induced toxicity: antioxidant and histological study in mice.

Venkatesan, C; Sarathi, M; Balasubramanian, G; Thomas, John; Balachander, V; Babu, V Sarath; Bilal, S Mohammed Yusuf; Majeed, S Abdul; Madan, N; Raj, N Sundar; Vimal, S; Nambi, K S N; Hameed, A S Sahul

Venkatesan, C; Sarathi, M; Balasubramanian, G; Thomas, John; Balachander, V; Babu, V Sarath; Bilal, S Mohammed Yusuf; Majeed, S Abdul; Madan, N; Raj, N Sundar; Vimal, S; Nambi, K S N; Hameed, A S Sahul.

Affiliation

Venkatesan C; 1Aquaculture Biotechnology Division, OIE Reference Laboratory for WTD, Department of Zoology, C. Abdul Hakeem College, Melvisharam, Vellore District, Tamil Nadu, India.

Hum Exp Toxicol ; 33(4): 336-59, 2014 Apr.

Article in En | MEDLINE | ID: mdl-23857030

Subject(s)

Antioxidants/pharmacology; Elapid Venoms/toxicity; Triterpenes/pharmacology; Animals; Catalase/metabolism; Elapid Venoms/antagonists & inhibitors; Glutathione/metabolism; Glutathione Peroxidase/metabolism; Glutathione Transferase/metabolism; Lethal Dose 50; Mice; Plant Extracts/pharmacology; Superoxide Dismutase/metabolism

Key words

CAT; GSH; GSH-PX; GST; LPO; Leucas aspera Linn.; Naja naja naja; SOD; antiserum; cobra; mice

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Full text: 1 Database: MEDLINE Main subject: Triterpenes / Elapid Venoms / Antioxidants Language: En Journal: Hum Exp Toxicol Year: 2014 Type: Article Affiliation country: India

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