The effect of grape seed extract on the pharmacokinetics of dextromethorphan in healthy volunteers.

Goey, Andrew K L; Meijerman, Irma; Beijnen, Jos H; Schellens, Jan H M

Goey, Andrew K L; Meijerman, Irma; Beijnen, Jos H; Schellens, Jan H M.

Affiliation

Goey AK; Department of Pharmaceutical Sciences, Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, The Netherlands, andrewgoey@hotmail.com.

Eur J Clin Pharmacol ; 69(11): 1883-90, 2013 Nov.

Article in En | MEDLINE | ID: mdl-23881421

Subject(s)

Antitussive Agents/pharmacokinetics; Dextromethorphan/pharmacokinetics; Grape Seed Extract/pharmacology; Adult; Antitussive Agents/urine; Cross-Over Studies; Cytochrome P-450 CYP2D6/metabolism; Dextromethorphan/urine; Dextrorphan/urine; Drug Interactions; Female; Healthy Volunteers; Humans; Male; Middle Aged; Young Adult

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Full text: 1 Database: MEDLINE Main subject: Antitussive Agents / Dextromethorphan / Grape Seed Extract Type of study: Clinical_trials Language: En Journal: Eur J Clin Pharmacol Year: 2013 Type: Article

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