Effects of praeruptorin A and praeruptorin C, a racemate isolated from Peucedanum praeruptorum, on MRP2 through the CAR pathway.

Zhou, Xunian; Bi, Huichang; Jin, Jing; Niu, Lu; Cai, Dake; Deng, Rongrong; Li, Yuhua; Wang, Yongtao; Huang, Min

Zhou, Xunian; Bi, Huichang; Jin, Jing; Niu, Lu; Cai, Dake; Deng, Rongrong; Li, Yuhua; Wang, Yongtao; Huang, Min.

Affiliation

Zhou X; Laboratory of Drug Metabolism and Pharmacokinetics, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China.

Planta Med ; 79(17): 1641-7, 2013 Nov.

Article in En | MEDLINE | ID: mdl-24214834

Subject(s)

Apiaceae/chemistry; Coumarins/pharmacology; Drugs, Chinese Herbal/pharmacology; Herb-Drug Interactions; Multidrug Resistance-Associated Proteins/metabolism; Receptors, Cytoplasmic and Nuclear/metabolism; Constitutive Androstane Receptor; Coumarins/isolation & purification; Hep G2 Cells; Humans; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins/genetics; RNA, Messenger/metabolism; Real-Time Polymerase Chain Reaction; Transfection; Up-Regulation

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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Drugs, Chinese Herbal / Receptors, Cytoplasmic and Nuclear / Apiaceae / Coumarins / Multidrug Resistance-Associated Proteins / Herb-Drug Interactions Language: En Journal: Planta Med Year: 2013 Type: Article Affiliation country: China

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