Antidepressant and anxiolytic properties of the methanolic extract of Momordica charantia Linn (Cucurbitaceae) and its mechanism of action.

Ishola, I O; Akinyede, A A; Sholarin, A M

Ishola, I O; Akinyede, A A; Sholarin, A M.

Affiliation

Ishola IO; Department of Pharmacology, Therapeutics and Toxicology, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Lagos, Nigeria.
Akinyede AA; Department of Pharmacology, Therapeutics and Toxicology, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Lagos, Nigeria.
Sholarin AM; Department of Pharmacology, Therapeutics and Toxicology, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Lagos, Nigeria.

Drug Res (Stuttg) ; 64(7): 368-76, 2014 Jul.

Article in En | MEDLINE | ID: mdl-24227474

Subject(s)

Anti-Anxiety Agents/pharmacology; Antidepressive Agents/pharmacology; Cucurbitaceae/chemistry; Momordica charantia/chemistry; Plant Extracts/pharmacology; Animals; Anti-Anxiety Agents/chemistry; Antidepressive Agents/chemistry; Depression/drug therapy; Hindlimb Suspension/methods; Male; Methanol/chemistry; Mice; Motor Activity/drug effects; Plant Extracts/chemistry; Swimming

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Full text: 1 Database: MEDLINE Main subject: Anti-Anxiety Agents / Plant Extracts / Cucurbitaceae / Momordica charantia / Antidepressive Agents Language: En Journal: Drug Res (Stuttg) Year: 2014 Type: Article Affiliation country: Nigeria

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