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Renal improvement by zinc in diabetic mice is associated with glucose metabolism signaling mediated by metallothionein and Akt, but not Akt2.
Sun, Weixia; Wang, Yuehui; Miao, Xiao; Wang, Yonggang; Zhang, Li; Xin, Ying; Zheng, Shirong; Epstein, Paul N; Fu, Yaowen; Cai, Lu.
Affiliation
  • Sun W; First Hospital, Jilin University, Jilin 130021, China; Kosair Children's Hospital Research Institute, Department of Pediatrics, University of Louisville, KY 40202, USA.
  • Wang Y; Second Hospital, Jilin University, Jilin 130041, China.
  • Miao X; Kosair Children's Hospital Research Institute, Department of Pediatrics, University of Louisville, KY 40202, USA; Second Hospital, Jilin University, Jilin 130041, China.
  • Wang Y; Kosair Children's Hospital Research Institute, Department of Pediatrics, University of Louisville, KY 40202, USA; China-Japan Union Hospital, Jilin University, Jilin 130031, China.
  • Zhang L; First Hospital, Jilin University, Jilin 130021, China.
  • Xin Y; Kosair Children's Hospital Research Institute, Department of Pediatrics, University of Louisville, KY 40202, USA; Norman Bethune Medical College, Jilin University, Jilin 130021, China.
  • Zheng S; Kosair Children's Hospital Research Institute, Department of Pediatrics, University of Louisville, KY 40202, USA.
  • Epstein PN; Kosair Children's Hospital Research Institute, Department of Pediatrics, University of Louisville, KY 40202, USA; Department of Pharmacology and Toxicology, University of Louisville, KY 40202, USA.
  • Fu Y; First Hospital, Jilin University, Jilin 130021, China. Electronic address: fuyaowen@medmail.com.cn.
  • Cai L; Kosair Children's Hospital Research Institute, Department of Pediatrics, University of Louisville, KY 40202, USA; Department of Pharmacology and Toxicology, University of Louisville, KY 40202, USA. Electronic address: L0cai001@louisville.edu.
Free Radic Biol Med ; 68: 22-34, 2014 Mar.
Article in En | MEDLINE | ID: mdl-24296248
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Full text: 1 Database: MEDLINE Main subject: Zinc / Diabetic Nephropathies / Proto-Oncogene Proteins c-akt / Metallothionein Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: Free Radic Biol Med Year: 2014 Type: Article Affiliation country: United States
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Full text: 1 Database: MEDLINE Main subject: Zinc / Diabetic Nephropathies / Proto-Oncogene Proteins c-akt / Metallothionein Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: Free Radic Biol Med Year: 2014 Type: Article Affiliation country: United States