Vitamin A deficiency impairs adaptive B and T cell responses to a prototype monovalent attenuated human rotavirus vaccine and virulent human rotavirus challenge in a gnotobiotic piglet model.

Chattha, Kuldeep S; Kandasamy, Sukumar; Vlasova, Anastasia N; Saif, Linda J

Chattha, Kuldeep S; Kandasamy, Sukumar; Vlasova, Anastasia N; Saif, Linda J.

Affiliation

Chattha KS; The Food Animal Health Research Program, Department of Veterinary Preventive Medicine, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, Ohio, United States of America.

PLoS One ; 8(12): e82966, 2013.

Article in En | MEDLINE | ID: mdl-24312675

Subject(s)

B-Lymphocytes/immunology; Rotavirus Vaccines/immunology; Rotavirus/immunology; T-Lymphocytes/immunology; Vitamin A Deficiency/immunology; Vitamin A Deficiency/physiopathology; Animals; CD8-Positive T-Lymphocytes/metabolism; Humans; Interferon-alpha/metabolism; Interleukin-10/metabolism; Interleukin-12/metabolism; Rotavirus/pathogenicity; Swine; Vitamin A Deficiency/metabolism

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Full text: 1 Database: MEDLINE Main subject: Vitamin A Deficiency / B-Lymphocytes / T-Lymphocytes / Rotavirus / Rotavirus Vaccines Type of study: Prognostic_studies Language: En Journal: PLoS One Year: 2013 Type: Article Affiliation country: United States

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