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In vitro identification of cytochrome P450 isoforms responsible for the metabolism of 1-hydroxyl-2,3,5-trimethoxy-xanthone purified from Halenia elliptica D. Don.
Feng, Ru; Zhou, Xuelin; Tan, Xiang-Shan; Or, Penelope M Y; Hu, Tao; Fu, Jie; Ma, Jing-Yi; Huang, Min; He, Chi-Yu; Shi, Jian-Gong; Che, Chun-Tao; Yeung, John H K; Wang, Yan.
Affiliation
  • Feng R; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China.
  • Zhou X; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.
  • Tan XS; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China.
  • Or PM; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.
  • Hu T; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.
  • Fu J; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China.
  • Ma JY; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China.
  • Huang M; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China.
  • He CY; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China.
  • Shi JG; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China.
  • Che CT; Department of Medicinal Chemistry & Pharmacognosy (MC 781), UIC College of Pharmacy, Chicago, IL 60612-7231, USA.
  • Yeung JH; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.
  • Wang Y; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China. Electronic address: wangyan@imm.ac.cn.
Chem Biol Interact ; 210: 12-9, 2014 Mar 05.
Article in En | MEDLINE | ID: mdl-24380714
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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas Main subject: Plants, Medicinal / Microsomes, Liver / Gentianaceae / Cytochrome P-450 Enzyme System / Xanthones Type of study: Diagnostic_studies Country/Region as subject: Asia Language: En Journal: Chem Biol Interact Year: 2014 Type: Article Affiliation country: China
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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas Main subject: Plants, Medicinal / Microsomes, Liver / Gentianaceae / Cytochrome P-450 Enzyme System / Xanthones Type of study: Diagnostic_studies Country/Region as subject: Asia Language: En Journal: Chem Biol Interact Year: 2014 Type: Article Affiliation country: China