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Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.
Stribl, Carola; Samara, Aladin; Trümbach, Dietrich; Peis, Regina; Neumann, Manuela; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Rathkolb, Birgit; Wolf, Eckhard; Beckers, Johannes; Horsch, Marion; Neff, Frauke; Kremmer, Elisabeth; Koob, Sebastian; Reichert, Andreas S; Hans, Wolfgang; Rozman, Jan; Klingenspor, Martin; Aichler, Michaela; Walch, Axel Karl; Becker, Lore; Klopstock, Thomas; Glasl, Lisa; Hölter, Sabine M; Wurst, Wolfgang; Floss, Thomas.
Affiliation
  • Stribl C; Helmholtz Zentrum München, Institute of Developmental Genetics, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.
  • Samara A; Helmholtz Zentrum München, Institute of Developmental Genetics, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.
  • Trümbach D; Helmholtz Zentrum München, Institute of Developmental Genetics, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.
  • Peis R; Helmholtz Zentrum München, Institute of Developmental Genetics, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.
  • Neumann M; Institute of Neuropathology, Schmelzbergstrasse 12, CH-8091 Zurich, Switzerland.
  • Fuchs H; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum München, Ingolstaedter Landstrasse 1, 85764 Neuherberg, Germany.
  • Gailus-Durner V; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum München, Ingolstaedter Landstrasse 1, 85764 Neuherberg, Germany.
  • Hrabe de Angelis M; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum München, Ingolstaedter Landstrasse 1, 85764 Neuherberg, Germany; Technische Universität München, c/o Helmholtz Zentrum München, 85764 Neuherberg, Germany; German Center for Vertigo and Balance Disorders, Ludwig-Maximilians-Un
  • Rathkolb B; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum München, Ingolstaedter Landstrasse 1, 85764 Neuherberg, Germany; Gene Center, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Wolf E; Gene Center, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
  • Beckers J; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum München, Ingolstaedter Landstrasse 1, 85764 Neuherberg, Germany; Technische Universität München, c/o Helmholtz Zentrum München, 85764 Neuherberg, Germany.
  • Horsch M; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum München, Ingolstaedter Landstrasse 1, 85764 Neuherberg, Germany.
  • Neff F; Institute of Pathology, German Mouse Clinic, Helmholtz Zentrum München, Ingolstaedter Landstrasse 1, 85764 Neuherberg, Germany.
  • Kremmer E; Helmholtz Institut für Molekulare Immunologie (IMI), Helmholtz Zentrum München, 85764 Neuherberg, Germany.
  • Koob S; Buchmann Institute for Molecular Life Sciences, Mitochondrial Biology, Max-von-Laue-Strasse 15, 60438 Frankfurt am Main, Germany; Mitochondriale Biologie, Zentrum für Molekulare Medizin, Goethe Universität Frankfurt am Main, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.
  • Reichert AS; Buchmann Institute for Molecular Life Sciences, Mitochondrial Biology, Max-von-Laue-Strasse 15, 60438 Frankfurt am Main, Germany; Mitochondriale Biologie, Zentrum für Molekulare Medizin, Goethe Universität Frankfurt am Main, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany; Mitochondriale Biolo
  • Hans W; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum München, Ingolstaedter Landstrasse 1, 85764 Neuherberg, Germany; Molecular Nutritional Medicine, Else Kröner Fresenius Center and ZIEL Research Center for Nutrition and Food Science, Technische Universität München, Gregor-Men
  • Rozman J; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum München, Ingolstaedter Landstrasse 1, 85764 Neuherberg, Germany; Molecular Nutritional Medicine, Else Kröner Fresenius Center and ZIEL Research Center for Nutrition and Food Science, Technische Universität München, Gregor-Men
  • Klingenspor M; Molecular Nutritional Medicine, Else Kröner Fresenius Center and ZIEL Research Center for Nutrition and Food Science, Technische Universität München, Gregor-Mendel-Strasse 2, 85350 Freising-Weihenstephan, Germany.
  • Aichler M; Research Unit Analytical Pathology, Institute of Pathology, Helmholtz Zentrum München, 85764 Neuherberg, Germany.
  • Walch AK; Research Unit Analytical Pathology, Institute of Pathology, Helmholtz Zentrum München, 85764 Neuherberg, Germany.
  • Becker L; Institute of Experimental Genetics, German Mouse Clinic, Helmholtz Zentrum München, Ingolstaedter Landstrasse 1, 85764 Neuherberg, Germany; Department of Neurology, Friedrich-Baur-Institute, Ludwig-Maximilians-Universität, Ziemssenstrasse 1a, 80336 Munich, Germany.
  • Klopstock T; Research Unit Analytical Pathology, Institute of Pathology, Helmholtz Zentrum München, 85764 Neuherberg, Germany; Department of Neurology, Friedrich-Baur-Institute, Ludwig-Maximilians-Universität, Ziemssenstrasse 1a, 80336 Munich, Germany; Deutsches Zentrum für Neurodegenerative Erkrankungen e. V. (
  • Glasl L; Helmholtz Zentrum München, Institute of Developmental Genetics, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.
  • Hölter SM; Helmholtz Zentrum München, Institute of Developmental Genetics, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany; Technische Universität München, c/o Helmholtz Zentrum München, 85764 Neuherberg, Germany.
  • Wurst W; Helmholtz Zentrum München, Institute of Developmental Genetics, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany; Technische Universität München, c/o Helmholtz Zentrum München, 85764 Neuherberg, Germany; Deutsches Zentrum für Neurodegenerative Erkrankungen e. V. (DZNE), Site Munich, Schillerstr
  • Floss T; Helmholtz Zentrum München, Institute of Developmental Genetics, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany; Technische Universität München, c/o Helmholtz Zentrum München, 85764 Neuherberg, Germany. Electronic address: tfloss@helmholtz-muenchen.de.
J Biol Chem ; 289(15): 10769-10784, 2014 Apr 11.
Article in En | MEDLINE | ID: mdl-24515116
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Full text: 1 Database: MEDLINE Main subject: Gene Expression Regulation / DNA-Binding Proteins / Amyotrophic Lateral Sclerosis / Mitochondria Language: En Journal: J Biol Chem Year: 2014 Type: Article Affiliation country: Germany
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Full text: 1 Database: MEDLINE Main subject: Gene Expression Regulation / DNA-Binding Proteins / Amyotrophic Lateral Sclerosis / Mitochondria Language: En Journal: J Biol Chem Year: 2014 Type: Article Affiliation country: Germany