Inhalation administration of valerena-4,7(11)-diene from Nardostachys chinensis roots ameliorates restraint stress-induced changes in murine behavior and stress-related factors.

Takemoto, Hiroaki; Omameuda, Yuka; Ito, Michiho; Fukuda, Tatsuo; Kaneko, Shuji; Akaike, Akinori; Kobayashi, Yoshinori

Takemoto, Hiroaki; Omameuda, Yuka; Ito, Michiho; Fukuda, Tatsuo; Kaneko, Shuji; Akaike, Akinori; Kobayashi, Yoshinori.

Affiliation

Takemoto H; School of Pharmacy, Kitasato University.

Biol Pharm Bull ; 37(6): 1050-5, 2014.

Article in En | MEDLINE | ID: mdl-24882416

Subject(s)

Behavior, Animal/drug effects; Hypnotics and Sedatives/therapeutic use; Nardostachys/chemistry; Sesquiterpenes/therapeutic use; Stress, Psychological/drug therapy; Administration, Inhalation; Animals; Cerebral Cortex/drug effects; Cerebral Cortex/metabolism; Corticosterone/blood; Dopamine/metabolism; Hypnotics and Sedatives/administration & dosage; Hypnotics and Sedatives/isolation & purification; Hypnotics and Sedatives/pharmacokinetics; Hypothalamo-Hypophyseal System/drug effects; Male; Mice, Inbred Strains; Pituitary-Adrenal System/drug effects; Plant Roots/chemistry; Restraint, Physical; Serotonin/metabolism; Sesquiterpenes/administration & dosage; Sesquiterpenes/isolation & purification; Sesquiterpenes/pharmacokinetics; Stress, Psychological/metabolism

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Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas / Aromoterapia Main subject: Sesquiterpenes / Stress, Psychological / Behavior, Animal / Nardostachys / Hypnotics and Sedatives Type of study: Prognostic_studies Language: En Journal: Biol Pharm Bull Year: 2014 Type: Article

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