Engagement of Toll-like receptor 2 enhances interleukin (IL)-17(+) autoreactive T cell responses via p38 mitogen-activated protein kinase signalling in dendritic cells.

Wei, R; Dong, L; Xiao, Q; Sun, D; Li, X; Nian, H

Wei, R; Dong, L; Xiao, Q; Sun, D; Li, X; Nian, H.

Affiliation

Wei R; Tianjin Medical University Eye Hospital and Eye Institute, Tianjin, China.

Clin Exp Immunol ; 178(2): 353-63, 2014 Nov.

Article in En | MEDLINE | ID: mdl-24965660

Subject(s)

Autoimmunity; Dendritic Cells/immunology; Dendritic Cells/metabolism; Signal Transduction; Th17 Cells/immunology; Th17 Cells/metabolism; Toll-Like Receptor 2/metabolism; p38 Mitogen-Activated Protein Kinases/metabolism; Animals; Autoimmune Diseases/genetics; Autoimmune Diseases/immunology; Autoimmune Diseases/metabolism; Cell Lineage/genetics; Cytokines/biosynthesis; Cytokines/genetics; Dendritic Cells/drug effects; Epitopes, T-Lymphocyte/immunology; Female; Inflammation Mediators/metabolism; Mice; Peptidoglycan/pharmacology; RNA, Messenger/genetics; RNA, Messenger/metabolism

Key words

DCs; EAU; Th17 cells; p38 MAPK

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Full text: 1 Database: MEDLINE Main subject: Dendritic Cells / Signal Transduction / Autoimmunity / P38 Mitogen-Activated Protein Kinases / Toll-Like Receptor 2 / Th17 Cells Language: En Journal: Clin Exp Immunol Year: 2014 Type: Article Affiliation country: China

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