The Cape Chacma baboon is not suitable for evaluating human targeted anti-GPVI agents.

Janse van Rensburg, Walter J; Badenhorst, Philip N; Roodt, Jan P

Janse van Rensburg, Walter J; Badenhorst, Philip N; Roodt, Jan P.

Affiliation

Janse van Rensburg WJ; Department of Hematology and Cell Biology, University of the Free State , Bloemfontein , South Africa .

Platelets ; 26(6): 552-7, 2015.

Article in En | MEDLINE | ID: mdl-25165849

Subject(s)

Antibodies, Monoclonal/pharmacology; Platelet Aggregation Inhibitors/pharmacology; Platelet Membrane Glycoproteins/antagonists & inhibitors; Amino Acid Substitution; Animals; Antibodies, Monoclonal/therapeutic use; Base Sequence; Collagen/metabolism; Collagen/pharmacology; Drug Evaluation, Preclinical; Humans; Models, Animal; Molecular Sequence Data; Papio ursinus; Platelet Aggregation/drug effects; Platelet Aggregation/physiology; Platelet Aggregation Inhibitors/therapeutic use; Platelet Membrane Glycoproteins/chemistry; Platelet Membrane Glycoproteins/genetics; Platelet Membrane Glycoproteins/metabolism; Polymorphism, Single Nucleotide; Sequence Alignment

Key words

Animal model; anti-GPVI Basic

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Platelet Aggregation Inhibitors / Platelet Membrane Glycoproteins / Antibodies, Monoclonal Language: En Journal: Platelets Year: 2015 Type: Article Affiliation country: South Africa

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google