Insights into the antiatherogenic molecular mechanisms of andrographolide against Porphyromonas gingivalis-induced atherosclerosis in rabbits.

Al Batran, Rami; Al-Bayaty, Fouad; Al-Obaidi, Mazen M Jamil; Ashrafi, Amer

Al Batran, Rami; Al-Bayaty, Fouad; Al-Obaidi, Mazen M Jamil; Ashrafi, Amer.

Affiliation

Al Batran R; Center of Periodontology Studies, Faculty of Dentistry, Universiti Teknologi MARA (UiTM), 40450, Shah Alam, Selangor Darul Ehsan, Malaysia.

Naunyn Schmiedebergs Arch Pharmacol ; 387(12): 1141-52, 2014 Dec.

Article in En | MEDLINE | ID: mdl-25172523

Subject(s)

Anti-Inflammatory Agents/pharmacology; Atherosclerosis/prevention & control; Diterpenes/pharmacology; Porphyromonas gingivalis/pathogenicity; Animals; Anti-Inflammatory Agents/administration & dosage; Aorta/drug effects; Aorta/pathology; Atherosclerosis/microbiology; Atorvastatin; Disease Models, Animal; Diterpenes/administration & dosage; Dose-Response Relationship, Drug; Heptanoic Acids/pharmacology; Intercellular Adhesion Molecule-1/metabolism; Lipid Peroxidation/drug effects; Male; Plaque, Atherosclerotic/microbiology; Plaque, Atherosclerotic/prevention & control; Pyrroles/pharmacology; Rabbits; Vascular Cell Adhesion Molecule-1/metabolism

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Full text: 1 Database: MEDLINE Main subject: Porphyromonas gingivalis / Diterpenes / Atherosclerosis / Anti-Inflammatory Agents Language: En Journal: Naunyn Schmiedebergs Arch Pharmacol Year: 2014 Type: Article Affiliation country: Malaysia

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