Catechins induced acute promyelocytic leukemia cell apoptosis and triggered PML-RAR&#945; oncoprotein degradation.

Zhang, Li; Chen, Qiu-Sheng; Xu, Peng-Peng; Qian, Ying; Wang, Ai-Hua; Xiao, Dan; Zhao, Yan; Sheng, Yan; Wen, Xiang-Qin; Zhao, Wei-Li

Catechins induced acute promyelocytic leukemia cell apoptosis and triggered PML-RARα oncoprotein degradation.

Zhang, Li; Chen, Qiu-Sheng; Xu, Peng-Peng; Qian, Ying; Wang, Ai-Hua; Xiao, Dan; Zhao, Yan; Sheng, Yan; Wen, Xiang-Qin; Zhao, Wei-Li.

J Hematol Oncol ; 7: 75, 2014 Oct 01.

Article in En | MEDLINE | ID: mdl-25270015

Subject(s)

Apoptosis/drug effects; Catechin/pharmacology; Leukemia, Promyelocytic, Acute/pathology; Oncogene Proteins, Fusion/drug effects; Animals; Blotting, Western; Cell Line, Tumor; Cell Survival/drug effects; Flow Cytometry; Humans; In Situ Nick-End Labeling; Male; Mice; Mice, Nude; Oncogene Proteins, Fusion/metabolism; Tea; Xenograft Model Antitumor Assays

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Leukemia, Promyelocytic, Acute / Catechin / Oncogene Proteins, Fusion / Apoptosis Language: En Journal: J Hematol Oncol Year: 2014 Type: Article

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google