Substance P protects against hyperoxic-induced lung injury in neonatal rats.

Huang, Bo; Li, Qing; Xu, Shuhong; Tian, Mingyang; Zhen, Xinghui; Bi, Yunxia; Xu, Feng

Huang, Bo; Li, Qing; Xu, Shuhong; Tian, Mingyang; Zhen, Xinghui; Bi, Yunxia; Xu, Feng.

Affiliation

Huang B; 1Pediatric Intensive Care Unit, The First People's Hospital of Zunyi , Zunyi , China.

Exp Lung Res ; 41(1): 12-20, 2015 Feb.

Article in En | MEDLINE | ID: mdl-25275819

Subject(s)

Bronchopulmonary Dysplasia/prevention & control; Hyperoxia/complications; Neurotransmitter Agents/therapeutic use; Substance P/therapeutic use; Animals; Animals, Newborn; Bronchopulmonary Dysplasia/enzymology; Bronchopulmonary Dysplasia/etiology; Drug Evaluation, Preclinical; Edema/etiology; Edema/prevention & control; Enzyme Activation/drug effects; Extracellular Signal-Regulated MAP Kinases/metabolism; Female; Glutathione Peroxidase/metabolism; Hyperoxia/enzymology; Lung/enzymology; Malondialdehyde/metabolism; NF-E2-Related Factor 2/metabolism; Neurotransmitter Agents/pharmacology; Pregnancy; Random Allocation; Rats, Sprague-Dawley; Substance P/pharmacology; Superoxide Dismutase/metabolism

Key words

Substance P; apoptosis; hyperoxic lung injury; oxidative stress

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Full text: 1 Database: MEDLINE Main subject: Bronchopulmonary Dysplasia / Substance P / Neurotransmitter Agents / Hyperoxia Type of study: Etiology_studies Language: En Journal: Exp Lung Res Year: 2015 Type: Article Affiliation country: China

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